While on their separate vacations, each member of the BAU receives a clue from a psychopathic killer who challenges them to save his next victim.
Eli Stone 2×13: Flight Path
Eli decides to help a heart transplant patient after seeing her in a plane crash vision. A further vision indicates someone from the law firm being involved in the crash as well.
Naruto 13×25: Regroup!
Shizune, Ino, Lee and Tenten arrive and Kakashi, Shizune and Yamato discuss about a strategy to seal the Sanbi and rescue Yukimaru. Meanwhile, Kabuto and Rinji notice Guren’s care for Yukimaru and become concerned.
Smallville 2×23: Exodus (2)
A sense of foreboding surrounds Smallville as Clark must choose between staying with Lana and his family or fulfilling his destiny to rule the Earth. Lex and Helen prepare for their marriage, and Chloe considers Lionel’s offer to investigate Clark.
The Simpsons 11×22: Behind the Laughter
A la VH-1’s Behind the Music, a behind the scenes look is taken at the Simpson family’s rise to fame, their successful years together and then their feud which resulted in a breakup and solo careers for the family members.
Criminal Minds 2×23: No Way Out (2): The Evilution of Frank
When the prolific serial killer Frank returns and murders Gideon’s girlfriend, Gideon takes off to find him without telling the team where he is going. The BAU must then profile Gideon as well as Frank to find both of them.
Numb3rs 3×24: The Janus List
In the midst of investigating a serious bomb threat, Don and Charlie uncover a secret that could change their lives and the lives of the team forever.
The Simpsons 20×16: Eeny Teeny Maya Moe
Moe develops an internet relationship with a woman named Maya; when the two agree to meet face to face Moe is shocked to discover that Maya is three feet tall.
Heroes 1×23: How to Stop an Exploding Man
Can Sylar be stopped? Will Linderman’s vision live on with Nathan? What will it take for Peter to save the world? What sacrifices will be made? With all the horrible predictions unfolding before them, the heroes face moments of pain and peril in Kirby Plaza.
Discovering that NTAC is behind the disease plaguing the 4400s, Tom and Diana try to get to the bottom of NTAC's cover-up, while Kyle considers turning himself in.
Discovering that NTAC is behind the disease plaguing the 4400s, Tom and Diana try to get to the bottom of NTAC's cover-up, while Kyle considers turning himself in.
4400s across the world are coming down with strange and life threatening illnesses. Tom and Diana learn a horrible secret that the government may have directly caused the illnesses of the 4400s.
Tom and Diana investigate Edwin Mayuya, a 4400 who has the ability is to heal damaged fetal chromosomes while in utero. Unfortunately, it turns out this man is responsible for the slaughter of an entire clinic. Tom and Diana are torn apart over their different opinions.
Tom and Diana investigate a 4400 who has released a plague that has wiped out an entire town's population. Meanwhile, a Washington D.C. lobbyist joins the 4400 Center in order to add some political muscle to the movement.
When Tom arrives at NTAC, he learns that no one has ever heard of the 4400. Tom and Diana track down a man to a museum, and during the chase, Tom finds a mysterious lab that only he can see.
Maia sees a vision of Jordan Collier's death. Kyle's frightening blackouts are disrupting Tom's personal life. Diana is asked to hand over Maia's diary to NTAC.
A school teacher terrifies parents with her ability to inspire talents within students. Meanwhile, Richard and Lily are confronted by police, and Jordan warns Shawn not to overuse his healing gift.
Gary Navarro, a minor league baseball player, finds that he is hearing everyone's unspoken thoughts. His new found ability quickly drives him to the edge of madness. When he seeks help from NTAC, the higher-ups are more interested in how he can unearth information about Jordan Collier, than how they can assist Gary with getting his life back.
It's been one year since the 4400 returned. After a period of intense medical observation, Tom has returned to NTAC in a limited capacity, assigned only to desk duty. Diana, having been through a series of inept partners, finally finds a way to cut through the red tape and get Tom back, all while in the midst of formally adopting Maia.
Richard, Lily and their child are still living in meager conditions in a mountain cabin far away from Jordan. Jordan has now closed Arcadia Estates, and is on the verge of opening "The 4400 Center", a place for non-members of the 4400 to discover "the 4400 within themselves". Collier becomes Shawn's guardian, and enlists him to heal important benefactors of the Center.